There is no one free from worldly worries.

Literal

Transient-world's worries [possessive-の] not-exist person [topic-は] not-exist.

浮世 means 'the floating world / this transient life' — a Buddhist-influenced concept central to Japanese aesthetics. ~のない人はない is a double negative meaning 'there is no person who doesn't have.' An aphoristic observation.