悲(かな)し()い() kanashii知(し)ら()せ() shiraseに ni彼(かれ) kareは wa食(しょく)欲(よく) shokuyokuが gaなくなった nakunatta。 The sad news made him lose his appetite. Literal Sad news [by-に] he [topic-は] appetite [subject-が] disappeared. 食欲がなくなった means 'appetite disappeared.' 悲しい知らせに marks the cause. A concrete physical effect of emotional distress. bodyhealthsadnessemotions~なくなる (cease to)
悲(かな)し()い() kanashii知(し)ら()せ() shiraseに ni彼(かれ) kareは wa食(しょく)欲(よく) shokuyokuが gaなくなった nakunatta。 The sad news made him lose his appetite. Literal Sad news [by-に] he [topic-は] appetite [subject-が] disappeared. 食欲がなくなった means 'appetite disappeared.' 悲しい知らせに marks the cause. A concrete physical effect of emotional distress. bodyhealthsadnessemotions~なくなる (cease to)