She used her paid leave to go skiing.

Literal

She [topic-は] paid-leave [object-を] utilizing, skiing [to-に] went.

有給休暇 (ゆうきゅうきゅうか, 'paid leave') is a formal work compound. 利用して ('utilizing') provides the means. スキーに行く is a standard leisure expression. The sentence combines work and leisure topics naturally.