。
She spoke with tears in her eyes.
Literal
She [topic-は] eyes [at-に] tears [object-を] floating spoke.
目に涙を浮かべて — 浮かべる (うかべる, 'to float, to show on the surface') is the causative of 浮かぶ, meaning 'to have tears well up in one's eyes.' The te-form sets the emotional backdrop for 話した.