She grabbed his hand.

Literal

She [topic-は] his [genitive-の] hand [object-を] grabbed.

つかむ ('grab, seize, grasp') is the everyday verb for taking hold firmly of something — distinct from 持つ ('hold, carry') and 握る ('grip, clench'). The action implies sudden or intentional grabbing, often with some force or urgency. Common in physical-action narratives.