You need permission to put up posters like this, and besides, it ruins the town's appearance!

Literal

This-kind-of poster [object-を] paste [for-には] permission [subject-が] necessary [copula-ですし], in-the-first-place town [possessive-の] beauty [object-を] damages!

だいいち 'in the first place, besides' escalates the argument. 美観を損なう 'to damage the aesthetic/beauty' — 美観 'scenic beauty' + 損なう 'to damage.' ~ですし gives a reason and implies there are more. The speaker is indignant about unauthorized posters.