、。
She's responsible, so I can always count on her.
Literal
She [topic-は] sense-of-responsibility [subject-が] exists [because-ので], I [topic-は] always her [about-のことを] can-rely-on.
責任感がある means 'to have a sense of responsibility' — 責任 (responsibility) + 感 (sense/feeling) + がある (exists). The ので provides the reason in a softer, more objective way than から. 頼りにできる means 'can rely on' — 頼り (reliance) + に + できる (can do). The いつでも ('anytime, always') emphasizes the unconditional nature of the trust.