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She arrived at school on time despite the blizzard.
Literal
She [topic-は] blizzard [despite-にもかかわらず] on-time school [at-に] arrived.
吹雪 (ふぶき) means 'blizzard' or 'snowstorm' — 吹 (blow) + 雪 (snow). にもかかわらず marks the concessive: 'despite the blizzard.' 時間どおりに means 'on time' or 'on schedule' — どおり means 'in accordance with.' The sentence highlights determination: she made it to school punctually even in extreme weather.