She's very cynical about life.

Literal

She [topic-は] life [toward-に対して] very cynical.

冷笑的 (れいしょうてき) literally breaks down as 冷 ('cold') + 笑 ('laugh') + 的 ('-like') — 'of a cold-laughing nature,' i.e. cynical or derisive. This kind of three-character compound (kanji + kanji + 的) is a productive way Japanese builds expressive adjectives from descriptive imagery. The word itself is more common in written or formal contexts than in casual conversation.