。
She's always troubled by headaches.
Literal
She [topic-は] always headaches [from-で] is-troubled.
頭痛 (ずつう, 'headache') with で marks the cause of her suffering. 悩む (なやむ, 'to be troubled, to suffer, to agonize') is stronger than 困る ('to be in trouble') — it implies ongoing distress. The 常に + ~ている pattern describes a chronic condition.