。
She doesn't waste time.
Literal
She [topic-は] time [object-を] waste does-not-make.
AをBにする ('make A into B') is a productive Japanese pattern for changing the state of something — here X時間 + を + 無駄 + に + する = 'make time wasted / waste time.' The idiom 時間を無駄にする ('waste time') and its negation are common — efficient use of time is a recurring cultural value. むだ (無駄) means 'wasteful, futile, pointless'; the kanji form is more formal, the kana more conversational. Negation ~しない frames it as a habitual disposition.