。
She isn't home right now.
Literal
She [topic-は] now home [at-に] is-not.
いる ('to be, exist [animate]') is one of the two existence verbs Japanese requires you to choose between: いる for animate beings, ある for inanimate things. The negative polite いません handles the basic 'not present.' Note that 家にいる is the natural way to say 'be home' in Japanese — there's no separate 'be home' verb; you say 'be at house.' The locative に on 家 marks the place of existence, not motion or destination.