。
She should be there by now.
Literal
She [topic-は] around-this-time is-arrived [supposed-to-はず] is.
~はず ('should, supposed to, expected to') marks an outcome the speaker expects based on logic or prior information — not an evidential guess like ~だろう, but an expectation grounded in reasoning. 'She left at 3, the trip takes an hour, so she should be there by now.' Combined with the resulting-state ~ている on 着く ('arrive'), the prediction lands on the state of having arrived.