In the end, she didn't come.

Literal

She [topic-は] in-the-end did-not-come.

結局 ('in the end, after all, ultimately') is the discourse adverb you reach for to summarize an outcome after a process or sequence of expectations. It commonly precedes the verdict on what happened, often paired with a slight sense of resignation or final-tally finality: 結局やめた ('ended up quitting'), 結局買わなかった ('didn't buy it after all'). In novels it functions almost like a chapter-closing sigh.