。
She lost her handbag.
Literal
She [topic-は] handbag [object-を] lost.
紛失する ('to lose, mislay') is a slightly formal Sino-Japanese verb specifically for losing items — distinct from 失う ('to lose, be deprived of'), which is broader and covers loss of life, opportunities, and abstract things. 紛失 belongs to the register of insurance claims, lost-and-found offices, and official forms — somewhat more formal than the casual なくす ('lose, miss').