。
She looks really unwell.
Literal
She [topic-は] very condition [subject-が] bad [seems-そう] [as-に] appears.
Two evidentials stack here: 悪そう ('looks bad' from sensory impression) plus に見える ('appears as') — a slightly redundant pile-up that emphasizes how vivid the impression is. 具合が悪い ('condition is bad') is the everyday way to say 'feel unwell, off color' — covers everything from a mild headache to outright sickness, with context picking the severity.