？
What satisfies your aesthetic sense?
Literal
Your beauty-awareness [object-を] satisfy-causative thing [topic-は] what [copula-です-question-か]?
美意識 ('aesthetic sense, sense of beauty') is a single compact word for the concept English takes a phrase to express. 満足させる is the causative of 満足する ('to be satisfied') — literally 'to make satisfied.' The nominalizer もの here refers to 'things that [satisfy],' with the relative clause modifying it. A philosophically-inclined question.