?。
What's really going on with you? You don't have your usual spark.
Literal
Really how-did [polite-んですか]? Usual [gen-の] energy [subj-が] not-exist [polite-です] [emph-よ].
ホント is a colloquial clipping of 本当 'really / truly,' written in katakana to mark an emphatic or slightly rougher tone. 覇気 'hegemonic spirit' has softened in contemporary Japanese to mean 'drive, ambition, vigor' — the kind of presence someone radiates when engaged. ~んですか is the explanatory/confirmatory question form (contraction of のですか), probing beneath surface facts for an underlying explanation — 'what's the story here?'