However, it's going to become necessary to factor in other things as well.

Literal

However other [gen-の] thing [also-も] consideration [into-に] put-[must-なければならなく] become [probably-だろう].

しかし 'however' opens the contrastive turn. 考慮に入れる '(to) put into consideration / take into account' is the formal collocation — 考慮 'consideration' + に + 入れる 'put in.' ~なければならなくなる combines the obligation pattern ~なければならない with なる 'to become,' giving 'to come to have to X / it will become necessary.' だろう supplies the predictive hedge 'probably.'