I think it's important to sharply distinguish between 'facts' and 'opinions'.
Literal
''Facts'' [and-と] ''opinions'' [object-を] sharply-distinguish [quotative-という] thing [topic-は] important thing is [quotative-と] think.
A prescriptive statement about critical thinking. 峻別する (しゅんべつする) is a formal verb meaning 'to sharply distinguish, strictly separate' — stronger than the everyday 区別する. The 峻 kanji literally means 'steep, severe'. ~ということは nominalizes the 'doing X' action, and the pattern ~と思う frames it as the speaker's opinion. Common in essay/editorial writing.