。
Those good-for-nothings got fired.
Literal
Those good-for-nothing [topic-は] fired became [emphasis-よ].
ろくでなし (good-for-nothing) with the contemptuous plural suffix ~ども marks strong disdain. クビになる (literally 'become a neck') is colloquial for getting fired — the neck metaphor comes from samurai-era beheading. よ at the end adds emphatic assertion.