There's no meat left in the refrigerator.

Literal

Refrigerator [in-には] meat [topic-は] is-not-remaining.

Double は: 冷蔵庫には and 肉は. The first marks the location as topic; the second marks the meat as a contrastive topic ('as for meat' — implying something else might be there). 残っていません uses the resulting-state ~ている + polite negative.