。
You can never be too kind to your parents.
Literal
Parents [toward-に対しては] no-matter-how kind-do [even-if-ても] too-much [nominalizer-こと] [topic-は] doesn't-exist.
どんなに~てもしすぎることはない means 'no matter how much you do X, it's never too much.' This is a set pattern for expressing that something is always warranted. に対して marks the recipients of the kindness. A proverbial statement about filial duty.