Elements C and D can be excluded because they have no bearing on arc generation.
Literal
Elements C [and-と] D [topic-は] arc [possessive-の] generation [for-には] unrelated [because-なので] exclude [subject-を] do-can.
A technical/mathematical register sentence. 無関係 ('unrelated / irrelevant') is a na-adjective. 排除する ('to exclude / eliminate'). The structure ~することができる ('can do X') is a formal equivalent to the potential form.