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What time is the pharmacy open until?
Literal
Pharmacy [topic-は] what-time [until-まで] is-open [polite-Q-か].
A practical everyday question built on ~ている (ongoing state) applied to 開く — 開いている means 'is in the opened state,' not 'is opening.' ~まで marks the endpoint, so 何時まで is literally 'until what hour.' Polite register suitable for speaking to shop staff.