。
Could you arrange a night sightseeing bus?
Literal
Night [gen-の] sightseeing bus [obj-を] arrange-[honorific favor-てくださいますか].
~てくださいますか is the honorific-polite request form — 下さる ('give (to me), do for me (honorific)') combined with ~ます and the question ~か. More polite than ~てください, appropriate for requesting service. 手配する ('arrange, make arrangements, organize') is used for logistical arrangements.