The question is whether she'll read my letter.

Literal

Problem [topic-は] she [subj-が] letter [obj-を] read-[favor-てくれる] [whether-かどうか] [copula-です].

~てくれるかどうか ('whether or not (she'll) do the favor of X') — an interesting stacking that preserves the benefactive nuance inside the embedded question. The speaker wants her to read and wonders if she will.