The cause of the problem lies in a lack of communication between departments.

Literal

Problem [poss-の] cause [topic-は] department-between [poss-の] communication [poss-の] lack [at-に] exists.

部署間 uses ~間 ('between, among') as a suffix. コミュニケーション is a loanword. 欠如 ('lack, absence') is formal Sino-Japanese. ~にある ('lies in') locates the cause. Three の particles chain together.