。
My eyes hurt.
Literal
Eye [subject-が] is-painful.
Textbook basic. The i-adjective 痛い ('painful, hurting') takes the painful body part as its subject with が — 'eye is-painful,' not 'I-feel-pain-in-eye.' です is the polite copula tacked onto the i-adjective; grammatically redundant but expected in polite register.