。
Do you have a license?
Literal
License [topic-は] [honorific-お]hold-持ち [question-ですか].
お持ち is the honorific form (sonkeigo) of 持つ ('to have, to hold'), formed by prefixing お and using the masu-stem. お持ちですか is a polite way to ask if someone possesses something. Commonly heard at shops when staff ask if you have a membership card: ポイントカードはお持ちですか.