、。
Speaking of Nagoya, have you ever been to Seto?
Literal
Nagoya [speak-of-と言えば], you [topic-は] Seto [to-へ] go [experience-たことがある] [polite-ますか].
~と言えば = 'speaking of X' — a topic-pivot marker. Used to shift from one topic to a related one. 瀬戸 (Seto) is a city in Aichi Prefecture famous for setomono (瀬戸物), pottery/ceramics. ~たことがある is the 'have experience of X-ing' construction.