漫画と日本の映画産業の関係は、ベストセラーとハリウッドの関係に似ている。

、。

The relationship between manga and Japan's film industry is similar to that of bestsellers and Hollywood.

Literal

Manga [and-と] Japan's film-industry's relationship [topic-は], best-sellers [and-と] Hollywood's relationship [to-に] resembles.

似る ('to resemble') takes its target with に, not を. Here the comparison is between two A-と-B relationships, so the sentence reads '[relationship 1] resembles [relationship 2].' The conjunctive と joins parallel nouns (manga and film industry) into one unit, distinct from the quotative or comparative と.