。
I've exhausted all my options.
Literal
I [topic-は] already all-strategies exhausted.
万策尽きた (ばんさくつきた, 'all strategies exhausted') — 万策 ('ten-thousand strategies' = every possible plan) + 尽きる ('to be exhausted, run out'). もう ('already') emphasizes that the point of no return has been reached. A dramatic declaration of helplessness.