I'm fed up with meetings these days, you know.

Literal

I [topic-は] these-days meetings [at-に] fed-up-am [emphasis-よ].

うんざりする is a 擬態語-derived verb expressing weariness, fatigue, being fed up. に marks the source of the weariness ('fed up AT meetings'). このごろ ('these days, recently') sets the time frame as ongoing recent. The final よ adds the conversational complain-to-someone tone.