The visitors are scheduled to arrive on the 18th and leave on the 20th.

Literal

Visitors [topic-は] 18th [at-に] come-[sequential-て], 20th [at-に] depart-[scheduled-ことになっている]

~ことになっている marks a pre-arranged schedule, rule, or agreed-upon plan — 'it's decided that X', 'X is supposed to happen'. More impersonal than ~ことにしている (the active decision form). 発つ (たつ) is a slightly formal verb for 'to depart (on a journey)', more evocative than the plain 出発する.