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Witch hazel tightens pores without drying the skin.
Literal
Witch-hazel [topic-は], drying-without [connective-ずに] pores [object-を] tightens.
A beauty/skincare product description. ウィッチヘーゼル ('witch hazel') is the katakana transliteration of the plant-based astringent. 乾燥させずに ('without causing drying') uses the causative させる in the classical negative connective ~ずに ('without doing'). 毛穴 (けあな, 'pores,' literally 'hair holes') is a skincare term. 引き締める (ひきしめる, 'to tighten / to firm up') is a compound verb: 引く (pull) + 締める (tighten).