一生を捧げる (dedicate one's life)

The set phrase X に + 一生を捧げる (also written 一生をささげる), 'to dedicate / devote one's whole life to X.' 捧げる ('to offer up, dedicate') has religious/reverential roots — the life itself is framed as an offering to the cause marked with に. Slightly elevated, ceremonial flavor — appropriate for talking about deep commitment to a cause or pursuit.